The Red Bull-owned squad and the sports betting company have partnered to help the latter make its Bundesliga debut.
At RB Leipzig's Red Bull Arena home stadium, the operator will announce its presence to spectators with LED board animations and goal-side Cam Carpets.
However, 888sport's marketing initiatives will concentrate on RB Leipzig's online platforms.
The RBL Predictor Game, which offers fans the chance to win prizes including autographed jerseys, VIP tickets, and season tickets, will also be presented by 888sport.
"As in the rest of football, we are always looking to strengthen in the area of partnerships, especially those who fit our philosophy and orientation," said Matthias Reichwald, RB Leipzig's Chief Commercial Officer.
"We're happy that 888sport regards us as a good partner for their initial step into the Bundesliga. We've found one of these in 888sport.
"888sport is a well-known brand that wants to expand both nationally and internationally, which perfectly aligns with our vision, and now we can take on this challenge together."
Pedro Barreda, Director of International Marketing and Head of Sponsorships at 888sport, said the same thing: "We're excited to partner with RB Leipzig and to be part of their growth for at least the next one and a half years.
"This relationship is a natural fit and will substantially help us with our ambitious objectives for the newly-regulated German sports betting industry," said RB Leipzig. "888 are a world leader in their sector, and RB Leipzig are one of the best teams in European football.
